Your data is the most important thing when you are working with Spotfire. If you are familiar with the data you want to analyze, chances increase that you can set up good visualizations and find interesting conclusions during the analysis.
In some cases, there are things you can do to prepare your data for analysis before you view it in Spotfire, for example, see
Data preparation in Microsoft Excel
. There are also a number of things you can do to get to know your data, and fix some issues before the analysis starts.